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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIST1H1E All Species: 34.55
Human Site: S86 Identified Species: 76
UniProt: P10412 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10412 NP_005312.1 219 21865 S86 R I K L G L K S L V S K G T L
Chimpanzee Pan troglodytes XP_001172808 221 22291 S87 R I K L G L K S L V S K G T L
Rhesus Macaque Macaca mulatta P40286 208 22075 S90 R I K L S L K S L V N K G I L
Dog Lupus familis XP_853847 290 29282 S141 R I K L G L K S L V S K G T L
Cat Felis silvestris
Mouse Mus musculus P43274 219 21959 S86 R I K L G L K S L V S K G T L
Rat Rattus norvegicus P15865 219 21969 S86 R I K L G L K S L V S K G T L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515094 223 22581 S86 R I K L G L K S L V A K G T L
Chicken Gallus gallus P08284 219 22026 S87 R I K L G L K S L V S K G T L
Frog Xenopus laevis P06893 220 22422 A90 R L K L A L K A L V T K G T L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P02255 256 26341 S96 F I K K Y L K S A V V N G K L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P19375 205 22145 S86 K G K G A S G S F K V N V Q A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.5 55.7 57.2 N.A. 94 95.4 N.A. 79.8 73.9 58.6 N.A. N.A. 43.3 N.A. N.A. 41.1
Protein Similarity: 100 87.3 68 62 N.A. 95.4 97.2 N.A. 87 79.4 66.3 N.A. N.A. 52.3 N.A. N.A. 50.6
P-Site Identity: 100 100 80 100 N.A. 100 100 N.A. 93.3 100 73.3 N.A. N.A. 53.3 N.A. N.A. 13.3
P-Site Similarity: 100 100 86.6 100 N.A. 100 100 N.A. 100 100 93.3 N.A. N.A. 53.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 19 0 0 10 10 0 10 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 10 0 10 64 0 10 0 0 0 0 0 91 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 82 0 0 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 10 0 100 10 0 0 91 0 0 10 0 82 0 10 0 % K
% Leu: 0 10 0 82 0 91 0 0 82 0 0 0 0 0 91 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 10 19 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Q
% Arg: 82 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 10 10 0 91 0 0 55 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 10 0 0 73 0 % T
% Val: 0 0 0 0 0 0 0 0 0 91 19 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _